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08/01/2021 – 2 FAPESP PhD fellowship open until 31-AGO
08/01/2021 – FAPESP Younger Investigator Award approved!
04/22/2021 – Chernobyl Trio paper published at Science!
04/10/2021 – Congrets Eliza for FAPESP grant
03/10/2021 – Congrets Lana for FAPESP grant
03/02/2021 – Welcome Letícia (Undergraduate Research Student)
01/24/2021 – BRAVE Novartis approved!
12/22/2020 – PRONON approved!
12/10/2020 – Aline’s work published at Sci Rep!
12/08/2020 – Marina’s IO review at Current Opinions published!
12/07/2020 – Welcome Bianca (Master Student)
11/06/2020 – Newton Advanced Fellowship Award approved
11/01/2020 – Welcome Sabrina (Staff Research)
10/30/2020 – ISR Grant for immunotherapy in RCC approved
10/20/2o2o – Congrats Guilherme for FAPESP grant
09/30/2020 – Molecular Oncology Workshop
09/01/2020 – Congrets Eliza for PIBIC/CNPq grant
08/01/2020 – Congrets Jamile for FAPESP grant
25/06/2020 – Welcome Camila, Carol, Cecília, and Lucas (Master Students)
10/06/2020 – Welcome Marina (PhD Student)
15/11/2019 – Welcome Eliza (Undergraduate Research Student)
21/10/2019 – Welcome Guilherme (Master Student)
15/09/2019 – Welcome Lana (Undergraduate Research Student)
12/08/2019 – Welcome Aline (Postdoc)
02/07/2019 – Welcome Jamile (Undergraduate Research Student)

Prolonged Evaluation of COVID-19 Vaccine Effectiveness in Healthcare Workers at a Public Tertiary Hospital: A Retrospective Cohort Study 01/04/2026
CONCLUSIONS: The vaccines provided limited long-term protection against SARS-CoV-2 infection and mild COVID-19. However, protection against severe disease and death remained substantial despite the circulation of multiple variants.
Guilherme Silveira Castro
Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model 01/04/2026
T helper 17 cells play essential roles in mucosal immunity and autoimmunity, yet the mechanisms that protect these cells from oxidative DNA damage remain poorly defined. Here we show, in a murine model, that the nucleotide excision repair sensor Xeroderma Pigmentosum Complementation Group C preserves genomic stability and metabolic fitness during T helper 17 cell […]
Jefferson Antônio Leite
Prevalence of venous extension in malignant adrenal neoplasia: beyond primary tumors and identification of a novel imaging sign 28/02/2026
CONCLUSION: Venous extension was less prevalent in metastatic adrenal lesions compared to ACCs. The edge sign may precede venous extension, especially in metastatic cases, indicating the nature of the lesion. These findings potentially may alter disease management, expediting the decision for surgery; however, prospective multicenter studies are needed to confirm their clinical impact.
Lais P D M Melges
Using Mendelian randomization to investigate etiologic heterogeneity across renal cell carcinoma subtypes 31/10/2025
CONCLUSION: These results highlight the heterogeneous nature of RCC etiology and the importance of considering histologic subtypes in etiologic and genetic studies.
Timothy D Winter
Capivasertib plus abiraterone in PTEN-deficient metastatic hormone-sensitive prostate cancer: CAPItello-281 phase III study 21/10/2025
CONCLUSIONS: Capivasertib plus abiraterone improves rPFS versus placebo plus abiraterone in PTEN-deficient mHSPC, on a background of ADT, with a 7.5-month improvement in median rPFS. AE profile was consistent with that of the individual agents. Patients with PTEN-deficient mHSPC benefit from dual blockade of the PI3K/AKT and AR pathways with capivasertib plus abiraterone.
K Fizazi

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