The Agilent xCELLigence real-time cell analysis (RTCA) dual-purpose (DP) system provides a powerful means to monitor cells in real-time without the potential artifacts generated by using labels. This noninvasive measurement allows detection of changes in adherence, morphology, and viability without needing to overexpress reporter and target proteins.
The Agilent xCELLigence E-Plate features a biosensor configuration that covers 80% of each well bottom surface area. The real-time measurement of impedance across the biosensors provides sensitive immediate detection of the cellular condition and response. This enables a wide array of potential applications including (but not limited to):
- Cell proliferation
- Cell quality
- Compound-mediated cytotoxicity
- Cell-mediated cytotoxicity
- Cell adhesion and spreading
- Functional monitoring of receptor tyrosine kinase and GPCR signaling
- Cell-mediated cytolysis
- Barrier function
- Viral quantification
For additional details, please, see the manufacture’s website, the datasheet, and the user guideline.
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